Cytokine production in children with urinary tract infection
Abstract
In order to reveal the role of cytokines in renal tissue damage in infants with urinary tract infection (UTI) 80 patients aged from 1 to 6 months were examined. Two groups of patients were determined: 1) with UTI and normal urodynamics, 2) with UTI and urodynamic disorders (VUR, hydronephrosis). In all of them urine concentration of tumor necrosis factor-a, interleukin-6 and -10 standardized to urinary creatinine concentrations were evaluated. As a result significant changes of cytokines were found dependent on UTI activity and urodynamic abnormalities.
About the Authors
S. . Paunova
РГМУ
Russian Federation
Russian Federation
A. . Kucherenko
НЦЗД РФ
Russian Federation
Russian Federation
I. . Smirnov
НЦЗД РФ
Russian Federation
Russian Federation
G. . Serova
РГМУ
Russian Federation
Russian Federation
I. . Donin
Морозовская ДГКБ; г. Москва
Russian Federation
Russian Federation
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Review
For citations:
Paunova S., Kucherenko A., Smirnov I., Serova G., Donin I. Cytokine production in children with urinary tract infection. Nephrology and Dialysis. 2008;10(1):51-55. (In Russ.)
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