Preview

Nephrology and Dialysis

Advanced search

Clinical significance of urine protein for early diagnostic of reflux-nephropathies in children

Abstract

In 60 children from 3 month to 14 years old with bladder-ureteral reflux (BUR) the level of some proteins (microalbumin, retinol-connecting protein, myoglobin) in urine was determined. The patients were divided into 2 groups: with primary and secondary BUR. A reciprocal correlation was found between the level of proteins in urine and the severity of BUR.

About the Authors

B. M. Mahachev
Дагестанская медицинская академия, г. Махачкала; Московский НИИ педиатрии и детской хирургии МЗ и СР РФ, г. Москва
Russian Federation


A. A. Korsunsky
Дагестанская медицинская академия, г. Махачкала; Московский НИИ педиатрии и детской хирургии МЗ и СР РФ, г. Москва
Russian Federation


I. M. Osmanov
Дагестанская медицинская академия, г. Махачкала; Московский НИИ педиатрии и детской хирургии МЗ и СР РФ, г. Москва
Russian Federation


V. V. Dlin
Дагестанская медицинская академия, г. Махачкала; Московский НИИ педиатрии и детской хирургии МЗ и СР РФ, г. Москва
Russian Federation


E. A. Filina
Дагестанская медицинская академия, г. Махачкала; Московский НИИ педиатрии и детской хирургии МЗ и СР РФ, г. Москва
Russian Federation


References

1. Аничкова И.В. Особенности течения пузырно-мочеточникового рефлюкса и рефлюкс-нефропатии в детском возрасте. Автореф. дисс.. канд. мед. наук. СПб., 1997: 18.

2. Cochat P., Dubourg L., Bouvier R. et al. Parenchymatous cicatrix and urinary tract infection: physiopathology and clinical implications. Arch Pediatr 1998; 5 (3): 290S-295S.

3. Goonasekera C.D., Shah V., Dillon M.J. Tubular proteinuria in reflux nephropathy: post ureteric reimplantation. Pediatr Nephrol 1996; 10 (5): 559-563.

4. Hanbury D.C., Calvin J. Proteinuria and enzymuria in vesicoureteric reflux. Br J Urol 1992; 70 (6): 603-609.

5. Jones C.L., Eddy A.A. Tubulointerstitial nephritis. Pediatr Nephrol 1992; 6 (6): 572-586.

6. Kaminska A., Jung A., Olszewski S. et al. Beta-2 microglobulinuria in children with vesico-ureteral reflux and recurrent urinary tract infections. Pol Merkuriusz Lek 2000; 8 (46): 240-241.

7. Konda R., Sakai K., Ota S. et al. Urinary excretion of epidermal growth factor in children with reflux nephropathy. J Urology 1997; 157 (6): 2282-2286.

8. Ota S., Konda R., Sakai K. et al. Renal function in children with reflux nephropathy foolowed up more than 10 years after disappearance of vesicoureferal reflux: usefulness of alfa 1-microglobulin as a marker to predict the prognosis of these children. Nippon Hinyokika Gakkai Zasshi 1996; 87 (11): 1236-1242.

9. Schulman S.L., Snyder H.M. Vesicoureteral reflux and reflux nephropathy in children. Curr Opin Pediatr 1993; 5 (2): 191-197.

10. Tomlinson P.A. Low molecular weight proteins in children with renal disease. Pediatr Nephrology 1992; 6 (6): 565-571.

11. Tomlinson P.A. The use of low molecular weight proteins in the diagnosis of renal tubular dysfunction in children. MD. The University of Aucklaund. 1996: 234.

12. Tomlinson P.A., Smellie J.M., Prescod N. et al. Differential excretion of urinary proteins in children with vesicoureteric reflux and reflux nephropathy. Pediatr Nephrology 1994; 8 (1): 21-25.

13. Valles P., Cruzado M. Renal functional reserve and microalbuminuria excretion in vesicoureteral reflux after surgery correction. Medicina (B Aires) 1993; 53 (6): 507-513.

14. Yen C.W., Chen D.H. Urinary tract infection in children. J Microbiol Immunol Infect 1999; 32 (3): 199-205.


Review

For citations:


Mahachev B.M., Korsunsky A.A., Osmanov I.M., Dlin V.V., Filina E.A. Clinical significance of urine protein for early diagnostic of reflux-nephropathies in children. Nephrology and Dialysis. 2005;7(1):41-45. (In Russ.)

Views: 5


Creative Commons License
This work is licensed under a Creative Commons Attribution 4.0 License.


ISSN 1680-4422 (Print)
ISSN 2618-9801 (Online)