Pathogenesis of renal scarring Review
Abstract
Proliferation of interstitial fibroblasts and excessive deposition of interstitial extracellular matrix leading to fibrosis is typical for progression of all renal diseases. Recent investigations show the crucial role of vasoactive, pro- and antyinflammatory, proapoptotic mediators and growth factors in renal scar formation. The review describes the main pathways of nephrosclerosis development in view of integral interaction of different mediators.
About the Author
S. S. Paunova
Российский государственный медицинский университет, г. Москва
Russian Federation
Russian Federation
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Review
For citations:
Paunova S.S. Pathogenesis of renal scarring Review. Nephrology and Dialysis. 2005;7(2):130-135. (In Russ.)
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