Prognostic importance of the early anaemia correction in patients with chronic renal failure on haemodialysis
Abstract
The aim of the work was to assess prognostic importance of early correction of anaemia in patients with chronic renal failure (CRF) on haemodialysis (HD). 117 patients participated in the trial. Patients of group I had Hb level ≤80 g/l just before the dialysis. Patients of group II (control) had Hb level ≥100 g/l. Patients of group I did not receive epoetin in pre-dialysis stage of CRF. Forty (90%) of 44 patients of group II received epoetin in pre-dialysis stage of CRF (during 6-8 months). Most (94,5%) patients of group I received epoetin from the day of beginning of haemodyalisis and 88,6% patients of group II continued epoetin-therapy after it, respectively. Echocardiography was performed to all patients. Cardiovascular death rate in group I was twice higher than that in group II, inspite of a stable target Ht level by the end of 6th month. The main causes of mortality in group I were acute coronary syndrome, heart failure and arrhythmias. A longterm persistent anaemia in pre-dialysis patients doubles the risk of cardiac death during haemodyalisis treatment.
About the Authors
L. U. Milovanova
Кафедра нефрологии и гемодиализа ФППО, клиника нефрологии, внутренних и профессиональных болезней ММА им. И.М. Сеченова, г. Москва
Russian Federation
Russian Federation
A. U. Nikolaev
Кафедра нефрологии и гемодиализа ФППО, клиника нефрологии, внутренних и профессиональных болезней ММА им. И.М. Сеченова, г. Москва
Russian Federation
Russian Federation
T. A. Kozlova
Кафедра нефрологии и гемодиализа ФППО, клиника нефрологии, внутренних и профессиональных болезней ММА им. И.М. Сеченова, г. Москва
Russian Federation
Russian Federation
V. V. Safonov
Кафедра нефрологии и гемодиализа ФППО, клиника нефрологии, внутренних и профессиональных болезней ММА им. И.М. Сеченова, г. Москва
Russian Federation
Russian Federation
Y. S. Milovanov
Кафедра нефрологии и гемодиализа ФППО, клиника нефрологии, внутренних и профессиональных болезней ММА им. И.М. Сеченова, г. Москва
Russian Federation
Russian Federation
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Review
For citations:
Milovanova L.U., Nikolaev A.U., Kozlova T.A., Safonov V.V., Milovanov Y.S. Prognostic importance of the early anaemia correction in patients with chronic renal failure on haemodialysis. Nephrology and Dialysis. 2004;6(1):54-57. (In Russ.)
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