Early renal allograft dysfunction as a major factor contributing the transplantation outcomes
https://doi.org/10.28996/1680-4422-2018-1-48-55
Abstract
Aim of the study: early renal allograft dysfunction (ERAD) is one of the more common complications of kidney transplantation. The aim of this study was the investigation of the prevalence of ERAD and it influence on the late transplant function and survival rate. Methods: we conducted retrospective, cohort, observational, comparative single center study. 295 renal transplant recipients were included to the study. Results: we found that the prevalence of ERAD was 24.1% (71/295). This complication was associated with decrease of 6 years cumulative kidney transplant survival from 80.75% in control group to 68.75% in study group. Besides, ERAD was associated with a late increase in the serum creatinine level to 130.3 (97-141.5) µmol/l versus 99.4 (80.5-122) µmol/l (р<0.001) and decrease eGFR from 68.48 (53-86.8) ml/min in control group to 50.15 (39.95-66.78) ml/min in study group (р<0.001).
About the Author
Kalachyk Aleh
9th city clinical hospital, Minsk, Republic of Belarus
Russian Federation
Russian Federation
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Review
For citations:
Aleh K. Early renal allograft dysfunction as a major factor contributing the transplantation outcomes. Nephrology and Dialysis. 2018;20(1):48-55. (In Russ.) https://doi.org/10.28996/1680-4422-2018-1-48-55
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