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Asymptomatic microscopic hematuria in adults - causes and differential diagnosis

https://doi.org/10.28996/1680-4422-2018-1-77-84

Abstract

The review presents current definitions for asymptomatic microscopic hematuria, recommended for clinical application in the Guidelines issued by several associations and societies, and the regulations for urine samples collection for accurate quantitative evaluation of microscopic hematuria. Detailed information about the prevalence of asymptomatic microscopic hematuria in adult patients depending on age and sex are provided according to the data from several large cohorts and screening trials. The causes of non-glomerular and glomerular microscopic hematuria are presented. Different laboratory tests and examination techniques recommended for the evaluation of patients with asymptomatic microscopic hematuria and differential diagnostic are discussed, as well as the indications and contraindications for particular examination techniques application depending on age and sex of the patients. The results of patient’s evaluation with different methods are shown. In addition, the work-up algorithm for the adult patients with asymptomatic microscopic hematuria, considering the need to rule out both urological and glomerular/interstitial disorders, is provided.

About the Authors

E. V. Zakharova
Moscow State University of Medicine and Dentistry, Nephrology; Russian Medical Academy of Continuous Postgraduate Education, Nephrology and Hemodialysis
Russian Federation


I. V. Samorodskaya
National Medical Center of Preventive Medicine
Russian Federation


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Review

For citations:


Zakharova E.V., Samorodskaya I.V. Asymptomatic microscopic hematuria in adults - causes and differential diagnosis. Nephrology and Dialysis. 2018;20(1):77-84. (In Russ.) https://doi.org/10.28996/1680-4422-2018-1-77-84

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ISSN 1680-4422 (Print)
ISSN 2618-9801 (Online)