Antyhypertensive effect of felodipine after kidney transplantation
Abstract
Antihypertensive effect of felodipine (plendil) was studied in 14 kidney graft recipients (10 men, 4 woman) aged from 20 to 55 years. The mean time after kidney transplantation was 22±4 months. The creatinine plasma level was normal only in 4 recipients, while in 10 of them it ranged between 0,14-0,38 mmol/l. The blood pressure (BP) was not higher than 170/100 mm Hg only in four patients , but in ten others it reached 240-210/120 mm Hg. Before starting plendil the patients has been treated with the combination of nifedipine and β- blocker (propranolol). The indication for the plendil treatment was caused by the absence of its antihypertensive effect. Plendil caused the decrease of BP almost to normal level in 10 from 14 patients. So we have found felodipin as to be a very effective antihypertensive agent after kidney transplantation.
About the Authors
O. N. Kotenko
Московский городской нефрологический центр при Городской Клинической больнице № 52
Russian Federation
Russian Federation
A. R. Bagdasaryan
Московский городской нефрологический центр при Городской Клинической больнице № 52
Russian Federation
Russian Federation
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Review
For citations:
Kotenko O.N., Bagdasaryan A.R. Antyhypertensive effect of felodipine after kidney transplantation. Nephrology and Dialysis. 1999;1(2-3):150-155. (In Russ.)
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