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Case of pregnancy favorable outcome in a patient receiving hemodialysis therapy. Case report

https://doi.org/10.28996/1680-4422-2017-4-531-539

Abstract

Pregnancy in patients with terminal renal failure receiving renal replacement therapy by hemodialysis is associated with high risks of complications at all stages of its development. Here we describe a case of qualified observation and treatment of a 39 years old patient with terminal renal failure and planned pregnancy, starting with pregravid preparation. Dialysis therapy promoted the normalization of the most important functions of the women’s body, including reproductive. At the time of the initiation of pregravid preparation, the duration of renal replacement therapy was twenty-two years. Conception occurred on the background of pregravid preparation. In the process of observation, adequate correction of the dialysis and drug therapy was carried out. This clinical case describes some complications that occur at the twelfth week of the pregnancy, such as anemia, cholestasis. Considering the high risk of premature birth from 18 weeks of gestation, the patient's maternal mode was limited to the bed-rest by being in a specialized gynecological hospital. Continuation of conservative therapy of pregnancy at the period of 23-24 weeks in the obstetric-gynecological clinic allowed the prolongation of the bearing of the fetus and the choice of the optimal method of delivery - cesarean section. The appointment of glucocorticoids at 23d and 25th weeks of pregnancy provided prevention of respiratory distress syndrome in the fetus. As a result, the mother and child were discharged in a good condition.

About the Authors

A. D. Putintseva
Federal State Budget Institution, A.M. Nikiforov Russian Center of Emergency and Radiation Medicine, Emergencies and Elimination of Consequences of Natural Disasters
Russian Federation


I. V. Zhdanova
Federal State Budget Institution, A.M. Nikiforov Russian Center of Emergency and Radiation Medicine, Emergencies and Elimination of Consequences of Natural Disasters
Russian Federation


O. E. Lavrinovich
Federal State Budget Institution, A.M. Nikiforov Russian Center of Emergency and Radiation Medicine, Emergencies and Elimination of Consequences of Natural Disasters
Russian Federation


S. V. Kuznetsov
Federal State Budget Institution, A.M. Nikiforov Russian Center of Emergency and Radiation Medicine, Emergencies and Elimination of Consequences of Natural Disasters
Russian Federation


R. R. Temirbulatov
State Budgetary Educational Institution of Higher Professional Education, First Pavlov State Medical University of Saint Petersburg under the Ministry of Health of the Russian Federation
Russian Federation


V. F. Bezhenar
State Budgetary Educational Institution of Higher Professional Education, First Pavlov State Medical University of Saint Petersburg under the Ministry of Health of the Russian Federation
Russian Federation


N. V. Leontieva
Federal State Budget Educational Institution of Higher Professional Education "North-West State Medical University. I.I. Mechnikov ", Ministry of Health of the Russian Federation
Russian Federation


References

1. Беспалова А.В., Бондаренко Т.В., Козловская Н.Л. и соавт. Успешное завершение беременности у пациентки с терминальной почечной недостаточностью, более 10 лет находящейся на лечении программным гемодиализом. Нефрология и диализ. 2014. Т.16. № 4: 485- 487. A.V. Bespalova, T.V. Bondarenko, N.L. Kozlovskaya. Successful pregnancy in a woman with end-stage renal disease and receiving long-term hemodialysis more than 10 years. Case report and review of the literature. Nephrology and dialysis. 2014. 16. 4: 485-487.

2. Краткая характеристика типовых лечебных режимов. Medical-Enc.ru 2007-2016. Kratkaya harakteristika tipovyh lechebnyh rezhimov. Medical-Enc.ru 2007-2016.

3. Нефрология: Руководство для врачей: в 2-х томах. Т.2/Под ред. И.А.Тареевой/ РАМН. М.:Медицина, 1995. - С.203-218. ISBN 5-225-00741-4. Nefrologiya: Rukovodstvo dlya vrachej: v 2-h tomah. T.2/Pod red.I.A.Tareevoj/ RAMN. -M.:Medicina, 1995. - S.203-218. ISBN 5-225-00741-4.

4. Нефрология: учебное пособие для послевузовского образования/ под ред. Е.М. Шилова. 2-е изд., испр. и доп. М.: ГЭОТАР Медиф, 2008: 486-497 ISBN 978-5-9704-0718-9. Nefrologiya: uchebnoe posobie dlya poslevuzovskogo obrazovaniya/ pod red. E.M. Shilova. - 2-e izd., ispr. i dop. - M.: GEHOTAR - Medif, 2008:. - S. 486 - 497. ISBN 978-5-9704-0718-9.

5. Руководство по диализу / Редакторы: Джон Т.Даугирдас, Питер Дж.Блейк, ТоддС.Инг/ Пер.с англ. под ред. А.Ю.Денисова ООО "Издательство "Триада", 2003. - С.683 - 696. ISBN 5-94789-041-0. ISBN 0-316-17381-9. Руководство по нефрологии/ под ред. Р.В.Шрайера; пер. с англ. под ред. Н.А.Мухина. М.: ГЭОТАР-Медиа, 2009: 345-358. Rukovodstvo po dializu / Redaktory: Dzhon T.Daugirdas, Piter Dzh.Blejk, ToddS. Ing/ Per.sangl. pod red. A. YU. Denisova OOO "Izdatel'stvo "Triada", 2003. - S.683 - 696. ISBN 5-94789-041-0. ISBN 0-316-17381-9. Rukovodstvo po nefrologii/ pod red. R.V.SHrajera; per. s angl. pod red. N.A. Muhina. - M.: GEHOTAR-Media, 2009: - S. 345-358.

6. Asamiya Y., Otsubo S., Matsuda Y. et al. The importance of low blood urea nitrogen levels in pregnant patients undergoing hemodialysis to optimize birth weight and gestational age. Kidney Int. 2009. 75(11): 1217-22.

7. Bagon JA, Vernaeve H, De Muylder X, et al. Pregnancy and dialysis. Am J Kidney Dis. 1998. 31: 756.

8. Barua M, Hladunewich M Keunen J, et al. Successful pregnancies on nocturnal home hemodialysis. Clin J Am Soc Nephrol. 2008. 3(2): 392-6. doi: 10.2215/CJN.04110907.

9. Cunningham FG, Cox SM, Harstad TW, et al. Chronic renal disease and pregnancy outcome. Am J Obstet Gynecol. 1990. 163: 453.

10. Chakhtoura Z., Meunier M., Caby J. et al. Gynecologic follow up of 129 women on dialysis and after kidney transplantation: A retrospective cohort study. European Journal of Obstetrics Gynecology and Reproductive Biology. 2015. 187: 1-5.

11. Demirci, C., Seziş Demirci, M., Aşçi, G., et al. Frequency and outcomes of pregnancy on nocturnal home haemodialysis. Turkish Nephrology, Dialysis and Transplantation Journal. 2017. 5: 202-209.

12. Gadallah MF, Ahmad B, Karubian F, Campese VM. Pregnancy in patients on chronic ambulatory peritoneal dialysis. Am J Kidney Dis. 1992. 20:407.

13. Giatras I, Levy DP, Malone FD, et al. Pregnancy during dialysis: case report and management guidelines. Nephrol Dial Transplant. 1998. 13: 3266.

14. Goldenberg R.L., Tamura T. Prepregnancy weight and pregnancy outcome J.A.M.A. 1996. 275. № 14: 1127-1128.

15. Holley JL, Reddy SS. Pregnancy in dialysis patients: a review of outcomes, complications, and management. NCBI. US National Library of Medicine. National Institute of Health. Semin Dial. 2003. 16(5): 384-8.

16. Hou S. Pregnancy in chronic renal insufficiency and end-stage renal disease. Am J Kidney Dis. 1999. 33: 235.

17. Hou S. Pregnancy in Women on Dialysis: Is Success a Matter of Time? Clin J Am Soc Nephrol. 2008. 3: 312-313 doi: 10.2215/CJN.00340108.

18. Hou SH. Frequency and outcome of pregnancy in women on dialysis. Am J Kidney Dis 1994. 23: 60.

19. Hou SH. Pregnancy in women on haemodialysis and peritoneal dialysis. Baillieres Clin Obstet Gynaecol. 1994: 8:481.

20. Jungers P, Chauveau D. Pregnancy in renal disease. Kidney Int. 1997. 52: 871.

21. Jesudason S, Grace BS, McDonald SP. Pregnancy outcomes according to dialysis commencing before or after conception in women with ESRD. Clin J Am Soc Nephrol. 2014. 9(1): 143-9.

22. Krupa FG, Faltin D, Cecatti JG, et al. Predictors of preterm birth. Int Gynaecol.Obstet. 2006. 94(1): 5-11. Epub 2006 May 24.

23. Leitich H., Brumbauer M., Kaider A. et al. Cervical length and dilation of the internal as detected by vaginal ultrasonography as markers for preterm delivery: a systematic review. Am. J. Obstet. Gynecol. 1999. Т. 181: 1465-1472.

24. Lim, T.S.C., Shanmuganathan, M., Wong, I., Goh, B.L. Successful multigravid pregnancy in a 42-year-old patient on continuous ambulatory peritoneal dialysis and a review of the literature. BMC Nephrol. 2017. 18: 108.

25. Maduell F., Moreso F., Pons M.,et al. for the ESHOL Study Group. High-Efficiency Postdilution Online Hemodiafiltration Reduces All-Cause Mortality in Hemodialysis Patients. JASN. 2013 ASN. 2012080875.

26. Mann H., Ernst E., Gladziwa U., et al. Changes in blood volume during dialysis are dependent upon the rate and amount of ultrafiltrate. ASAIO Trans. 1989. 35(3): 250-2.

27. Okundaye I, Abrinko P, Hou S. Registry of pregnancy in dialysis patients. Am J Kidney Dis. 1998. 31(5): 766-73.

28. Piccoli GB, Conijn A, Consiglio V, et al. Pregnancy in dialysis patients: is the evidence strong enough to lead us to change our counseling policy? Clin J Am Soc Nephrol. 2010. 5: 62.

29. Phyllis August, John Vella. Pregnancy in women with underlying renal disease. Walter Kluwer Health. UpToDate 17-Mar-2013.

30. Rocco M.V., Cheung A.K., Greene T.,Eknoyan G. for the Hemodialysis (HEMO) Study Group. The HEMO Study: applicability and generalizability. Nephrol Dial Transplant. 2005. 20(2): 278-284.

31. Sachdeva M, Barta V, Thakkar J, et al. Pregnancy outcomes in women on hemodialysis: a national survey. Clin Kidney J. 2017. 10(2): 276-281.

32. Toma H, Tanabe K, Tokumoto T, et al. Pregnancy in women receiving renal dialysis or transplantation in Japan: a nationwide survey. Nephrol Dial Transplant. 1999. 14: 1511.

33. THE Actim™ Partus versus the TLIIQ system as rapid response tests to aid in diagnosing preterm labor in symptomatic women. Institute of Health Economics: Preterm Labor in Symptomatic women. January 2008. ISSUE RA2-2008-01.

34. Volker J.J. Schettler, Egbert G.Schulz, Gerrit C.Hagenah, Claas L.Neumann. Successful completion of pregnancy using apheresis and a balanced dose of coagulation factors in the presence of high thrombophilia and Lp(a) levels in a woman with two previous abortion. Clin Kidney J. 2014. 7: 497-498.


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For citations:


Putintseva A.D., Zhdanova I.V., Lavrinovich O.E., Kuznetsov S.V., Temirbulatov R.R., Bezhenar V.F., Leontieva N.V. Case of pregnancy favorable outcome in a patient receiving hemodialysis therapy. Case report. Nephrology and Dialysis. 2017;19(4):531-539. (In Russ.) https://doi.org/10.28996/1680-4422-2017-4-531-539

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