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Predicting the results of kidney transplantation by factors associated with the condition of patients before surgery Part 2 - The results of multivariate analysis

Abstract

The aim of the study, materials and methods are described in the first part of the article. Results: Methods of multivariate analysis revealed the following significant predictors of ATP results associated with the condition of the patient before the surgery (р<0,05): for the life of the patient: hemoglobin level, albumin, ALT, cholesterol, smoking; for renal transplant: hemoglobin level, albumin, smoking; for chronic transplant nephropathy: smoking, hemoglobin level, ALT, comorbidity index.

About the Authors

A. G. Stolyar
Regional Clinical Hospital №1 Ekaterinburg
Russian Federation


L. N. Budkar
FBSI «Ekaterinburg medical scientific centre of prophylaxis and protection of health by the workers of industry enterprises» Russian consumers’ supervision
Russian Federation


S. I. Solodushkin
Ural Federal University; Ural Branch of the Russian Academy of Sciences
Russian Federation


References

1. Андрусев А.М., Титова Н.Л., Бикбов Б.Т., Томилина Н.А. Перитонеальный диализ: ранние предикторы отдаленных результатов. Нефрология и диализ. 2003. Т. 5. №4: 362-368.

2. Бикбов Б.Т., Кирхман В.В., Ушакова А.И., Камшилова Н.И., Томилина Н.А. Предикторы летального исхода у больных на гемодиализе. Нефрология и диализ. 2004. Т. 6. №2: 154 - 163.

3. Волгина Г.В., Перепеченных Ю.В., Бикбов Б.Т., и соавт. Факторы риска кардиваскулярных заболеваний у больных с хронической почечной недостаточностью. Нефрология и диализ. 2000. Т. 2. №4: 252-259.

4. Новикова Н.А., Гендлин Г.Е., Сторожаков Г.И., Томилина Н.А., Андрусев А.М. Выживаемость больных хронической терминальной почечной недостаточностью, получающих постоянный амбулаторный перитонеальный диализ. Клиническая нефрология. 2010. №4: 26-33.

5. Arnol M., Buturović-Ponikvar J., Kandus A. Association of Pretransplant Renal Replacement Therapy Duration With Outcome in Kidney Transplant Recipients: A Prevalent Cohort Study in Slovenia. Therapeutic Apheresis and Dialysis. DOI: 10.1111/j.1744-9987.2011.00943.x.

6. Bittar J., Cepeda P., de la Fuente J., et al. Renal transplantation in diabetic patients. Transplant Proc. 2006. Apr. 38(3): 895-8.

7. Boucek P., Saudek F., Pokorna E., et al. Kidney transplantation in type 2 diabetic patients: a comparison with matched non-diabetic subjects. Nephrol Dial Transplant. 2002. 17: 1678-1683.

8. Doyle S.E., Matas A.J., Gillingham K. and Rosenberg M.E. Predicting clinical outcome in the elderly renal transplant recipient. Kidney International. 2000. 57: 21442150; doi:10.1046/j.1523-1755.2000.00066.x.

9. Faravardeh A., Eickhoff M., Jackson S., et al. Predictors of graft failure and death in elderly kidney transplant recipients. Transplantation. 2013. 96. 12: 1089-1096.

10. Foley D.P., Patton P.R., Meier-Kriesche H.U et al. Long-term outcomes of kidney transplantation in recipients 60 years of age and older at the University of Florida. Clin Transpl. 2005: 101-9. http://www.ncbi.nlm.nih.gov/pubmed/.

11. Kasiske B.L., Gaston R.S., Gourishankar S., et. al. Long-term deterioration of kidney allograft function. Am J Transplant. 2005. 5: 1405-1414.

12. Kasiske B.L., Klinger D. Cigarette smoking in renal transplant recipients. J Am Soc Nephrol. 2000. 11: 753-759.

13. Kaysen G.A., Dubin J.A., Müller H-G., et al. Inflammation and reduced albumin synthesis associated with stable decline in serum albumin in hemodialysis patients. Kidney International. 65. №4: 1408-1415.

14. Lai X., Chen G., Qiu J., Wang C., Lizhong C. Recipient-Related Risk Factors for Graft Failure and Death in Elderly Kidney Transplant Recipients. PLOS. Published: November 12. 2014. DOI: 10.1371.

15. London G.M., Pannier B., Guerin A.P. at al. Alterations of left ventricular hypertrophy in and survival of patients receiving hemodialysis: follow-up of an interventional study. J Am Soc Nephrol. 2001 Dec. 12(12): 2759-67.

16. Lowrie E.G., Lew N.L. Death risk in hemodialysis patients: The predictive value of commonly measured variables and an evaluation of death rate differences between facilities. Am J Kidney Dis. 1990. 15: 458-482.

17. Mann J.F.E. What are the short-term and long-term consequences of anemia in CRF patients? Nephrol Dial Transplant. 1999. 14 (Suppl 2): 29-36.

18. Ojo A.O., Hanson J.A., Wolfe R.A., Leichtman A.B., Agodoa L.Y. and Port F.K. Long-term survival in renal transplant recipients with graft function. Kidney International.2000. 57, 307-313; doi:10.1046/j.1523-1755.2000.00816.x.

19. Orth S.R., Ogata H., Ritz E. Smoking and the kidney. Nephrology Dialysis Transplantation. 15. 10: 1509-1511.

20. Orth S.R., Schreier R.W., Ritz E. The renal risks of smoking. Kidney Int. 1997. 51: 1669-1677.

21. Sameiro-Faria M., Ribeiro S., Costa E., et al. Risk Factors for Mortality in Hemodialysis Patients: Two-Year Follow-Up Study. Disease Markers. 2013. 35. 6: 791-798. http://dx.doi.org/10.1155/2013/518945.

22. Silberberg J.S., Barre P.E., Prichard S.S., Sniderman A.D. Impact of left ventricular hypertrophy on survival in end-stage renal disease. Kidney Int. 1989 Aug. 36(2): 286-90.

23. Silberberg J.S., Rahal D.P., Patton R., Sniderman A.D. Role of anemia in the pathogenesis of left ventricular hypertrophy in end-stage renal disease. Am J Cardiol. 1989. № 64: 222-224.

24. Thorp M.L., Johnson E.S., Yang X., et al. Effect of anemia on mortality, cardiovascular hospitalizations and end-stage renal disease among patients with chronic kidney disease. Nephrology (Carlton). 2009. 14 (№ 2): P. 240-6.

25. Wang W., Li X.B., Yin H., et al. Factors affecting the long-term renal allograft survival. Chinese Medical Journal. 2011. 124. 8: 1181-1184.

26. Weiner D.E., Tighiouart H., Vlagopoulos P.T., et al. Effects of Anemia and Left Ventricular Hypertrophy on Cardiovascular Disease in Patients with Chronic Kidney Disease. J Am Soc Nephrol. 2005. № 16: 1803-1810.

27. Zoccali C., Benedetto F.A., Mallamaci F., et al. Left ventricular mass monitoring in the follow-up of dialysis patients: Prognostic value of left ventricular hypertrophy progression. Kidney Int. 2004. 65: 1492-1498.

28. http://newsnetwork.mayoclinic.org/discussion/mayo-clinic-study-shows-5-year-survival-of-diabetes-and-non-diabetes-patients-post-kidney-transplant/.


Review

For citations:


Stolyar A.G., Budkar L.N., Solodushkin S.I. Predicting the results of kidney transplantation by factors associated with the condition of patients before surgery Part 2 - The results of multivariate analysis. Nephrology and Dialysis. 2016;18(2):199-207. (In Russ.)

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