Factors influencing on arterial stiffness in ESRD patients on the different types of renal replacement therapy
Abstract
Arterial stiffness is a cardiovascular risk factor. The present research was performed in order to determine the factors influencing arterial stiffness in patients on hemodialysis and kidney transplant recipients. We examined 75 patients with ESRD (42 males and 33 females, age 49 ± 14 years) receiving renal replacement therapy (RRT), 58 of them were on hemodialysis, 17 had a functioning kidney transplant. The pulse wave velocity index (PWV) was used to assess arterial stiffness. It was calculated according to the contour of the peripheral pulse wave analysis. Correlation analysis in the group of dialysis patients revealed that PWV has negative correlation of medium strength with BMI (rs=-0.31, p=0.02). In the group of kidney transplant recipients correlation analysis showed that PWV correlated with the age of patients (rs=0.65; p=0.005) and the total cholesterol level (rs= 0.51; p= 0.04). Hemodialysis patients have increased arterial stiffness after dialysis, that was associated with the volume of ultrafiltration; stiffness is an additional factor of cardiovascular risk in these patients.
About the Authors
S. S. Bunova
Omsk State Medical Academy
Russian Federation
Russian Federation
O. A. Bilevich
Omsk State Medical Academy
Russian Federation
Russian Federation
S. B. Semchenko
Kabanov Omsk City Clinical Hospital № 1
Russian Federation
Russian Federation
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Review
For citations:
Bunova S.S., Bilevich O.A., Semchenko S.B. Factors influencing on arterial stiffness in ESRD patients on the different types of renal replacement therapy. Nephrology and Dialysis. 2014;16(3):359-363. (In Russ.)
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