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Assessment of the intima-media thickness of common carotid and femoral arteries and hemodynamic parameters in children with renal hypertension

Abstract

Renal arterial hypertension (AH) is an important medical and social problem. Uncontrolled AH increases the risk of development of cardiovascular diseases causing complications and increasing mortality in affected patients. One of the early cardiovascular complication markers in patients with AH is changes of the arterial wall – thickening of the arterial intima-media (IMT). A number of clinical studies in adults with cardiovascular disease show a high correlation between IMT and coronary and cerebrovascular complications. However, it is not yet clear if children with renal AH have the risk of the cardiovascular complications. The aim of the study was to evaluate the relationship of AH with indicators of blood vessels condition (carotid and femoral arteries) and hemodynamic parameters in children with renal diseases. In this group of children we found significant correlation of IMT of the common carotid and femoral arteries, level of AH and structure of the left ventricle measured with echocardiography. Hereby we suggest that in children with renal AH assessment of the arterial IMT thickening is a useful method for detection of the risk of cardiovascular complication. This method should be included in a comprehensive program of investigation of such children.

About the Authors

I. S. Kostushina
Research Center for Children Health, of the Russian Academy of Medical Sciences
Russian Federation


A. B. Sugak
Research Center for Children Health, of the Russian Academy of Medical Sciences
Russian Federation


O. I. Zrobok
Research Center for Children Health, of the Russian Academy of Medical Sciences
Russian Federation


T. V. Marghieva
Research Center for Children Health, of the Russian Academy of Medical Sciences
Russian Federation


I. V. Dvoryakovsky
Research Center for Children Health, of the Russian Academy of Medical Sciences
Russian Federation


A. N. Tsygin
Research Center for Children Health, of the Russian Academy of Medical Sciences
Russian Federation


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Review

For citations:


Kostushina I.S., Sugak A.B., Zrobok O.I., Marghieva T.V., Dvoryakovsky I.V., Tsygin A.N. Assessment of the intima-media thickness of common carotid and femoral arteries and hemodynamic parameters in children with renal hypertension. Nephrology and Dialysis. 2013;15(1):69-73. (In Russ.)

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