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Problems of pharmacotherapy and renal replacement therapy in patients with hepatorenal syndrome Review

Abstract

The review concerns hepatonephroprotective effects and complications of aquaretics (vaptans) – V2R antagonists of vasopressin, selective vasoconstrictors – V1R agonists of vasopressin, transjugular intrahepatic portosystemic shunt in patients with HRS. Albumin dialysis and PFAD show temporary effects and give possibility to perform liver transplantation. The transplantation is characterized by satisfactory 5-year survival and unusually high frequency of dialysis-dependent renal failure.

About the Author

A. Yu. Nikolaev
Department of Nephrology and Hemodialysis of the Russian Academy of Postgraduate Medical Education, Ministry of Health, Moscow
Russian Federation


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For citations:


Nikolaev A.Yu. Problems of pharmacotherapy and renal replacement therapy in patients with hepatorenal syndrome Review. Nephrology and Dialysis. 2012;14(3):160-163. (In Russ.)

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