Results of epidemiological investigation of nephrotic syndrome in children according to regional register

The aim of this study was to determine the incidence of nephrotic syndrome (NS) in children according to data of a regional register. A retrospective study was undertaken to describe demographic of all 90 children (54 boys and 36 girls) under 10 years diagnosed with NS in Voronezh region (Russia) over a 15-year period. The mean age of the onset was 3,25 years. The annual incidence of NS was 2,5 (1,8; 3,1) children per 100 000. The incidence of steroid sensitive NS was 2,0/100 000, of steroid resistant NS – 0,3/100 000, frequently relapsing and steroid dependent NS – 0,6/100 000, infrequently relapsing NS – 0,6/100 000. A negative correlation was found between the time courses of the incidence of steroid sensitive NS and of steroid resistant NS (r = –0,533, p = 0,041). The incidence of children with NS in Voronezh region of Russia is similar to overseas studies. The data of regional registry provide a more accurate picture of the epidemiology of NS.

нефротический синдром, заболеваемость, эпидемиология, региональный регистр, дети, nephrotic syndrome, epidemiology, regional register, children

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