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Том 12 №2 2010 год - Нефрология и диализ

Панцитопения и гемофагоцитарный синдром после трансплантации почки (Обзор литературы с клиническим наблюдением)


Прокопенко Е.И. Щербакова Е.О. Ватазин А.В. Гулимова С.Ю. Мартынюк А.П. Банина В.Б. Гаганов Л.Е.

Аннотация: Гемофагоцитарный синдром (ГФС) представляет собой редкий, угрожающий жизни синдром, характеризующийся лихорадкой, спленомегалией, панцитопенией и обнаружением в костном мозге и других тканях феномена гемофагоцитоза. В статье обобщены современные данные о патогенезе, клинической картине и подходах к лечению ГФС. Представлено также клиническое наблюдение фатального ГФС, ассоциированного с инфекциями, у больной с почечным трансплантатом.

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Ключевые слова: трансплантация почки, инфекционные осложнения, панцитопения, гемофагоцитарный синдром, kidney transplantation, infectious complications, pancytopenia, hemophagocytic syndrome

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