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Том 11 №2 2009 год - Нефрология и диализ

Безопасно ли внутривенное введение низкомолекулярного декстрана железа для коррекции анемии у больных с хронической почечной недостаточностью?


Ермоленко В.М. Михайлова Н.А. Батэрдэнэ С.

Аннотация: В сравнительном плане обобщены литературные данные о соединениях железа, используемых для в/в введения в первую очередь у больных с ХБП, находящихся на заместительной терапии. Особое внимание уделено зарегистрированному в конце 2008 г. низкомолекулярному декстрану железа (космоферу), уже успешно в течение длительного времени используемого в США и зарегистрированного кроме России еще в 50 странах. Анализ литературных данных позволил сделать однозначный вывод, что космофер по безопасности и эффективности практически не уступает зарекомендовавшему себя на российском рынке веноферу, а благодаря ряду структурных особенностей допускает одномоментное использование больших доз препарата, экономя рабочее время персонала и удешевляя лечение.

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Ключевые слова: хроническая болезнь почек, анемия, дефицит железа, соединения железа - космофер, венофер, феррлицит

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